Normally, an English Setter who is given proper care, nutrition, and exercise lives to about 12 years of age. With luck, they can go to age 14 or 15. An English Setter's prime is about age 4 to 7. If they have enjoyed good health, they don't start slowing down due to the effects of aging until about age 9.
It's common for English Setters to suffer from cancer at old age. Many senior English Setters will also develop "skin tumors", which are not real tumors, but fat/water lumps located on the inside of the fur. They are usually harmless and can be left alone, unless they increase in size or the dog is showing signs of pain or unease.
However, always have your vet have look at such lumps as they occur.
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